Reactome | STING:c-di-GMP [cytoplasmic vesicle membrane]

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STING:c-di-GMP [cytoplasmic vesicle membrane] Show undefined attributes

compartment	[Compartment:437051] cytoplasmic vesicle membrane
created	[InstanceEdit:2395982] Shamovsky, V, 2012-07-09
crossReference	[DatabaseIdentifier:12020761] Mondo:0005113
dbId	2395983
disease	[Disease:3134792] bacterial infectious disease
displayName	STING:c-di-GMP [cytoplasmic vesicle membrane]
hasComponent	[SimpleEntity:R-ALL-2395973] c-di-GMP [cytosol] [Complex:R-HSA-3134799] STING:STING [cytoplasmic vesicle membrane]
inDisease	true
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-2395983] STING:c-di-GMP [cytoplasmic vesicle membrane] - Mus musculus [Complex:R-RNO-2395983] STING:c-di-GMP [cytoplasmic vesicle membrane] - Rattus norvegicus [Complex:R-BTA-2395983] STING:c-di-GMP [cytoplasmic vesicle membrane] - Bos taurus [Complex:R-SSC-2395983] STING:c-di-GMP [cytoplasmic vesicle membrane] - Sus scrofa [Complex:R-DRE-2395983] STING:c-di-GMP [cytoplasmic vesicle membrane] - Danio rerio [Complex:R-XTR-2395983] STING:c-di-GMP [cytoplasmic vesicle membrane] - Xenopus tropicalis [Complex:R-GGA-2395983] STING:c-di-GMP [cytoplasmic vesicle membrane] - Gallus gallus [Complex:R-DME-2395983] STING:c-di-GMP [cytoplasmic vesicle membrane] - Drosophila melanogaster
isChimeric	false
literatureReference	[LiteratureReference:2395975] Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding
maxDepth	3
modified	[InstanceEdit:3248025] Shamovsky, V, 2013-04-05
name	STING:c-di-GMP
positivelyRegulates	[PositiveRegulation:9628328] Positive regulation by 'STING:c-di-GMP [cytoplasmic vesicle membrane]'
producedByEvent	[BlackBoxEvent:R-HSA-2396009] STING binds c-di-GMP - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2395983
updateTrackers	[UpdateTracker:9875394] Update Tracker - [Complex:2395983] STING:c-di-GMP [cytoplasmic vesicle membrane] - v44:[updateContainedComponent] [UpdateTracker:9881595] Update Tracker - [Complex:2395983] STING:c-di-GMP [cytoplasmic vesicle membrane] - v45:[addDisease, add_removeCompartment, add_removeHasComponent]

Referrals

(updatedInstance)	[UpdateTracker:9875394] Update Tracker - [Complex:2395983] STING:c-di-GMP [cytoplasmic vesicle membrane] - v44:[updateContainedComponent] [UpdateTracker:9881595] Update Tracker - [Complex:2395983] STING:c-di-GMP [cytoplasmic vesicle membrane] - v45:[addDisease, add_removeCompartment, add_removeHasComponent]
(output)	[BlackBoxEvent:R-HSA-2396009] STING binds c-di-GMP
(regulator)	[PositiveRegulation:9628328] Positive regulation by 'STING:c-di-GMP [cytoplasmic vesicle membrane]'