Reactome | 15S-HETE is oxidised to 15-oxoETE by 15-HEDH

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15S-HETE is oxidised to 15-oxoETE by 15-HEDH Show undefined attributes

authored	[InstanceEdit:2142839] Williams, MG, 2012-02-24
catalystActivity	[CatalystActivity:2161741] 15-hydroxyicosatetraenoate dehydrogenase activity of 15-HEDH [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2161780] Williams, MG, 2012-03-14
crossReference	[DatabaseIdentifier:12668399] RHEA:23261 [DatabaseIdentifier:12668400] RHEA:23265 [DatabaseIdentifier:9915902] RHEA:23260 [DatabaseIdentifier:9915886] RHEA:23264
dbId	2161789
displayName	15S-HETE is oxidised to 15-oxoETE by 15-HEDH
edited	[InstanceEdit:2142839] Williams, MG, 2012-02-24
eventOf	[Pathway:R-HSA-2142770] Synthesis of 15-eicosatetraenoic acid derivatives - Homo sapiens
input	[SimpleEntity:R-ALL-2142707] 15S-HETE [cytosol] [DefinedSet:R-ALL-428218] NAD(P)+ [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2162040] Expression of 15-lipoxygenase type-1 in human mast cells
maxDepth	1
modified	[InstanceEdit:9915896] D'Eustachio, Peter, 2024-07-17
name	15S-HETE is oxidised to 15-oxoETE by 15-HEDH (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD(P)(+) = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + NAD(P)H
output	[SimpleEntity:R-ALL-2142747] 15-oxoETE [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [DefinedSet:R-ALL-428206] NAD(P)H [cytosol]
precedingEvent	[Reaction:R-HSA-2161791] 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 - Homo sapiens
releaseDate	2012-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2569042] Rush, MG, 2012-11-10
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2161789
summation	[Summation:2161977] A 15-hydroxy-eicosatetraenoic acid dehydrogenase (15-HEDH) o...

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(hasEvent)

[Pathway:R-HSA-2142770] Synthesis of 15-eicosatetraenoic acid derivatives

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