Reactome | PGD2 is dehydrated to PGJ2

Schema > Reaction > Entries

authored	[InstanceEdit:2142839] Williams, MG, 2012-02-24
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:2161624] Williams, MG, 2012-03-14
crossReference	[DatabaseIdentifier:12668352] RHEA:50557 [DatabaseIdentifier:9915643] RHEA:50557
dbId	2161733
displayName	PGD2 is dehydrated to PGJ2
edited	[InstanceEdit:2142839] Williams, MG, 2012-02-24
eventOf	[Pathway:R-HSA-2162123] Synthesis of Prostaglandins (PG) and Thromboxanes (TX) - Homo sapiens
followingEvent	[Reaction:R-HSA-2161563] PGJ2 is isomerised to delta12-PGJ2 - Homo sapiens
input	[SimpleEntity:R-ALL-2161634] PGD2 [endoplasmic reticulum lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2161642] 15-Deoxy-delta 12,14-prostaglandins D2 and J2 are potent activators of human eosinophils
maxDepth	1
modified	[InstanceEdit:9915663] D'Eustachio, Peter, 2024-07-12
name	PGD2 is dehydrated to PGJ2 prostaglandin D2 => H2O + prostaglandin J2
output	[SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-2142674] PGJ2 [endoplasmic reticulum lumen]
precedingEvent	[Reaction:R-HSA-2161620] PGH2 is isomerised to PGD2 by PTGDS - Homo sapiens
releaseDate	2012-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2569042] Rush, MG, 2012-11-10
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2161733
summation	[Summation:2161606] Analogous to prostaglandin E2 (PGE2), dehydration of the pro...

(hasEvent)	[Pathway:R-HSA-2162123] Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
(precedingEvent)	[Reaction:R-HSA-2161563] PGJ2 is isomerised to delta12-PGJ2

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