Reactome | Activated FGFR2b mutants with enhanced ligand binding [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:2065930] Rothfels, K, 2012-01-24
crossReference	[DatabaseIdentifier:12020828] Mondo:0005497
dbId	2065931
disease	[Disease:2032940] bone development disease [Disease:1500689] cancer
displayName	Activated FGFR2b mutants with enhanced ligand binding [plasma membrane]
hasComponent	2 × [DefinedSet:R-HSA-2065925] FGFR2b mutant-binding FGFs [extracellular region] [SimpleEntity:R-ALL-190915] HS [extracellular region] [DefinedSet:R-HSA-2065923] p-8Y-FGFR2b dimers with enhanced ligand binding [plasma membrane]
inDisease	true
includedLocation	[Compartment:984] extracellular region
isChimeric	false
maxDepth	4
memberOf	[DefinedSet:R-HSA-5654747] Activated FGFR2 mutants [plasma membrane] - Homo sapiens
name	Activated FGFR2b mutants with enhanced ligand binding
producedByEvent	[Reaction:R-HSA-2033488] Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2065931
updateTrackers	[UpdateTracker:9891828] Update Tracker - [Complex:2065931] Activated FGFR2b mutants with enhanced ligand binding [plasma membrane] - v52:[updateContainedComponent]

(updatedInstance)	[UpdateTracker:9891828] Update Tracker - [Complex:2065931] Activated FGFR2b mutants with enhanced ligand binding [plasma membrane] - v52:[updateContainedComponent]
(output)	[Reaction:R-HSA-2033488] Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding
(hasMember)	[DefinedSet:R-HSA-5654747] Activated FGFR2 mutants [plasma membrane]

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