Reactome | Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA

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Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA Show undefined attributes

authored	[InstanceEdit:2046103] Garapati, P V, 2012-01-11
catalystActivity	[CatalystActivity:548822] fatty acid elongase activity of ELOVL2 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:2046086] Garapati, P V, 2012-01-11
dbId	2046095
displayName	Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA
edited	[InstanceEdit:2046103] Garapati, P V, 2012-01-11
eventOf	[Pathway:R-HSA-2046105] Linoleic acid (LA) metabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-2046097] Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-2046060] DTA-CoA [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-2046066] Malonyl-CoA [endoplasmic reticulum lumen] 2 × [SimpleEntity:R-ALL-113601] NADPH [endoplasmic reticulum lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2046031] The biosynthesis of delta-9,12,15,18-tetracosatetraenoic and of delta-6,9,12,15,18-tetracosapentaenoic acids by rat testes [LiteratureReference:2045979] Elongation of long-chain fatty acids [LiteratureReference:2046038] Fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in rat testicles
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA
orthologousEvent	[Reaction:R-PFA-2046095] Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA - Plasmodium falciparum [Reaction:R-DDI-2046095] Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA - Dictyostelium discoideum [Reaction:R-DME-2046095] Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA - Drosophila melanogaster [Reaction:R-GGA-2046095] Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA - Gallus gallus [Reaction:R-XTR-2046095] Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA - Xenopus tropicalis [Reaction:R-DRE-2046095] Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA - Danio rerio [Reaction:R-SSC-2046095] Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA - Sus scrofa [Reaction:R-BTA-2046095] Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA - Bos taurus [Reaction:R-CFA-2046095] Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA - Canis familiaris [Reaction:R-RNO-2046095] Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA - Rattus norvegicus [Reaction:R-MMU-2046095] Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA - Mus musculus
output	[SimpleEntity:R-ALL-159751] CO2 [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-162743] CoA-SH [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-2046048] TTA-CoA [endoplasmic reticulum lumen]
precedingEvent	[Reaction:R-HSA-2046083] Elongation of arachidonyl-CoA to docosatetraenoyl-CoA - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2046095
summation	[Summation:2045954] Docosatetraenoyl-CoA is elongated to tetracosatetraenoyl-CoA...

Referrals

(precedingEvent)	[Reaction:R-HSA-2046097] Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA
(hasEvent)	[Pathway:R-HSA-2046105] Linoleic acid (LA) metabolism

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