Reactome | eNOS binds NOSIP

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eNOS binds NOSIP Show undefined attributes

catalystActivity	[CatalystActivity:9911321] molecular sequestering activity of NOSIP [cytosol]
catalystActivityReference	[CatalystActivityReference:9911317] molecular sequestering activity of NOSIP [cytosol] NOSIP, a novel modulator of endothelial nitric oxide synthase activity
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:202104] Hemish, J, 2007-10-19 18:00:42
dbId	203553
displayName	eNOS binds NOSIP
eventOf	[Pathway:R-HSA-203754] NOSIP mediated eNOS trafficking - Homo sapiens
followingEvent	[Reaction:R-HSA-203680] eNOS:NOSIP translocation from caveolae to intracellular compartments - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-203636] NOSIP [cytosol] [Complex:R-HSA-203639] palmitoylated, myristoylated eNOS dimer [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:203644] NOSIP, a novel modulator of endothelial nitric oxide synthase activity
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	eNOS binds NOSIP
orthologousEvent	[Reaction:R-PFA-203553] eNOS binds NOSIP - Plasmodium falciparum [Reaction:R-DDI-203553] eNOS binds NOSIP - Dictyostelium discoideum [Reaction:R-DME-203553] eNOS binds NOSIP - Drosophila melanogaster [Reaction:R-SSC-203553] eNOS binds NOSIP - Sus scrofa [Reaction:R-BTA-203553] eNOS binds NOSIP - Bos taurus [Reaction:R-RNO-203553] eNOS binds NOSIP - Rattus norvegicus [Reaction:R-MMU-203553] eNOS binds NOSIP - Mus musculus
output	[Complex:R-HSA-203595] eNOS:NOSIP [plasma membrane]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2008-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:215470] Enikolopov, G, 2008-02-28 17:52:44 [InstanceEdit:9917333] Hill, David P, 2024-08-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-203553
summation	[Summation:203632] NOSIP (eNOS interacting protein) binds to the carboxyl-termi...
updateTrackers	[UpdateTracker:9919426] Update Tracker - [Reaction:203553] eNOS binds NOSIP - v90:[removeCatalystActivity]

Referrals

(updatedInstance)	[UpdateTracker:9919426] Update Tracker - [Reaction:203553] eNOS binds NOSIP - v90:[removeCatalystActivity]
(hasEvent)	[Pathway:R-HSA-203754] NOSIP mediated eNOS trafficking
(precedingEvent)	[Reaction:R-HSA-203680] eNOS:NOSIP translocation from caveolae to intracellular compartments