Reactome | p-6Y-FGFR2b C3 variant dimer [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:2029933] Rothfels, K, 2012-01-05
crossReference	[DatabaseIdentifier:12020782] Mondo:0001056
dbId	2029932
disease	[Disease:1500576] breast cancer [Disease:1500689] cancer [Disease:1500687] stomach cancer
displayName	p-6Y-FGFR2b C3 variant dimer [plasma membrane]
hasComponent	2 × [EntityWithAccessionedSequence:R-HSA-2029870] p-6Y-FGFR2b C3 variant [plasma membrane]
inDisease	true
isChimeric	false
literatureReference	[LiteratureReference:2023814] Aberrant receptor internalization and enhanced FRS2-dependent signaling contribute to the transforming activity of the fibroblast growth factor receptor 2 IIIb C3 isoform [LiteratureReference:2029817] Preferential alternative splicing in cancer generates a K-sam messenger RNA with higher transforming activity [LiteratureReference:2029811] Involvement of fibroblast growth factor receptor 2 isoform switching in mammary oncogenesis
maxDepth	2
memberOf	[DefinedSet:R-HSA-2029940] Activated overexpressed FGFR2 dimers [plasma membrane] - Homo sapiens
modified	[InstanceEdit:5654233] Rothfels, Karen, 2014-12-03
name	p-6Y-FGFR2b C3 variant dimer phosphorylated FGFR2b C3 variant dimer
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2029932
updateTrackers	[UpdateTracker:9890678] Update Tracker - [Complex:2029932] p-6Y-FGFR2b C3 variant dimer [plasma membrane] - v52:[addName]

(updatedInstance)	[UpdateTracker:9890678] Update Tracker - [Complex:2029932] p-6Y-FGFR2b C3 variant dimer [plasma membrane] - v52:[addName]
(hasMember)	[DefinedSet:R-HSA-2029940] Activated overexpressed FGFR2 dimers [plasma membrane]

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