Reactome | HLA-C Cw4 (group 2) [plasma membrane]

Schema > Complex > Entries

HLA-C Cw4 (group 2) [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-198909] HLA-C group 1 interacting with KIR2DL2/3 [plasma membrane] - Homo sapiens [Complex:R-HSA-199585] HLA-C group 2 interacting with KIR2DS1 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-198958] KIR2DL2/3 interacting with HLA-C group 1 (Cw4) - Homo sapiens [Reaction:R-HSA-199587] KIR2DS1 interacting with HLA-C group 2 (Cw4) - Homo sapiens
created	[InstanceEdit:198910] de Bono, B, 2007-07-08 12:43:29
dbId	198911
displayName	HLA-C Cw4 (group 2) [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-167743] B2M(21-119) [plasma membrane] [EntityWithAccessionedSequence:R-HSA-199595] HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [plasma membrane]
inDisease	false
inferredTo	[Complex:R-MMU-198911] HLA-C Cw4 (group 2) [plasma membrane] - Mus musculus [Complex:R-RNO-198911] HLA-C Cw4 (group 2) [plasma membrane] - Rattus norvegicus [Complex:R-CFA-198911] HLA-C Cw4 (group 2) [plasma membrane] - Canis familiaris [Complex:R-BTA-198911] HLA-C Cw4 (group 2) [plasma membrane] - Bos taurus [Complex:R-SSC-198911] HLA-C Cw4 (group 2) [plasma membrane] - Sus scrofa [Complex:R-DRE-198911] HLA-C Cw4 (group 2) [plasma membrane] - Danio rerio [Complex:R-GGA-198911] HLA-C Cw4 (group 2) [plasma membrane] - Gallus gallus
literatureReference	[LiteratureReference:199529] The KIR gene family: life in the fast lane of evolution [LiteratureReference:199545] Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones.
maxDepth	2
memberOf	[DefinedSet:R-HSA-2272698] HLA-C Cw3/HLA-C Cw4 [plasma membrane] - Homo sapiens
modified	[InstanceEdit:9827795] D'Eustachio, Peter, 2023-02-06
name	HLA-C Cw4 (group 2)
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-198911
updateTrackers	[UpdateTracker:9872446] Update Tracker - [Complex:198911] HLA-C Cw4 (group 2) [plasma membrane] - v41:[modifyName] [UpdateTracker:9905037] Update Tracker - [Complex:198911] HLA-C Cw4 (group 2) [plasma membrane] - v84:[add_removeHasComponent]

Referrals

(updatedInstance)	[UpdateTracker:9872446] Update Tracker - [Complex:198911] HLA-C Cw4 (group 2) [plasma membrane] - v41:[modifyName] [UpdateTracker:9905037] Update Tracker - [Complex:198911] HLA-C Cw4 (group 2) [plasma membrane] - v84:[add_removeHasComponent]
(hasComponent)	[Complex:R-HSA-198909] HLA-C group 1 interacting with KIR2DL2/3 [plasma membrane] [Complex:R-HSA-199585] HLA-C group 2 interacting with KIR2DS1 [plasma membrane] [Complex:R-HSA-2272773] KIR2DS1 oligomer:HLA-C (Cw4) [plasma membrane]
(input)	[Reaction:R-HSA-198958] KIR2DL2/3 interacting with HLA-C group 1 (Cw4) [Reaction:R-HSA-199587] KIR2DS1 interacting with HLA-C group 2 (Cw4)
(hasMember)	[DefinedSet:R-HSA-2272698] HLA-C Cw3/HLA-C Cw4 [plasma membrane]

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