Reactome | I(1,3,4,5,6)P5 transports from the ER lumen to the cytosol

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I(1,3,4,5,6)P5 transports from the ER lumen to the cytosol Show undefined attributes

authored	[InstanceEdit:1855226] Williams, MG, 2011-10-28
catalystActivity	[CatalystActivity:9954154] myo-inositol transmembrane transporter activity of unknown PI transporter [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:70101] cytosol
created	[InstanceEdit:1855226] Williams, MG, 2011-10-28
dbId	1855155
displayName	I(1,3,4,5,6)P5 transports from the ER lumen to the cytosol
edited	[InstanceEdit:1855226] Williams, MG, 2011-10-28
eventOf	[Pathway:R-HSA-1855215] IPs transport between ER lumen and cytosol - Homo sapiens
followingEvent	[Reaction:R-HSA-1855195] I(1,3,4,5,6)P5 transports from the cytosol to the ER lumen - Homo sapiens [Reaction:R-HSA-1855219] I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol - Homo sapiens [Reaction:R-HSA-1855223] I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol - Homo sapiens [Reaction:R-HSA-1855179] I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol - Homo sapiens
input	[SimpleEntity:R-ALL-2024008] I(1,3,4,5,6)P5 [endoplasmic reticulum lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1889919] The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization [LiteratureReference:1889864] Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase [LiteratureReference:1889938] Intracellular localization of human Ins(1,3,4,5,6)P5 2-kinase
maxDepth	1
modified	[InstanceEdit:9963234] D'Eustachio, Peter, 2025-08-13
name	I(1,3,4,5,6)P5 transports from the ER lumen to the cytosol
output	[SimpleEntity:R-ALL-994141] I(1,3,4,5,6)P5 [cytosol]
precedingEvent	[Reaction:R-HSA-1855195] I(1,3,4,5,6)P5 transports from the cytosol to the ER lumen - Homo sapiens [Reaction:R-HSA-1855225] IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen - Homo sapiens
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2012-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2562610] Wundenberg, Torsten, 2012-11-06 [InstanceEdit:9963235] Hill, David P, 2025-08-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1855155
summation	[Summation:2024014] Inositol 1,3,4,5,6-pentakisphosphate I(1,3,4,5,6)P5 transloc...
updateTrackers	[UpdateTracker:9964796] Update Tracker - [Reaction:1855155] I(1,3,4,5,6)P5 transports from the ER lumen to the cytosol - v94:[removeCatalystActivity]

Referrals

(updatedInstance)	[UpdateTracker:9964796] Update Tracker - [Reaction:1855155] I(1,3,4,5,6)P5 transports from the ER lumen to the cytosol - v94:[removeCatalystActivity]
(hasEvent)	[Pathway:R-HSA-1855215] IPs transport between ER lumen and cytosol
(precedingEvent)	[Reaction:R-HSA-1855219] I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol [Reaction:R-HSA-1855223] I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol [Reaction:R-HSA-1855179] I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol [Reaction:R-HSA-1855195] I(1,3,4,5,6)P5 transports from the cytosol to the ER lumen