Reactome | SULTs transfer (SO4)2- group to PREG

Schema > Reaction > Entries

SULTs transfer (SO4)2- group to PREG Show undefined attributes

catalystActivity	[CatalystActivity:176472] steroid sulfotransferase activity of SULTs active on pregnenolone [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:176534] D'Eustachio, P, 2006-03-08 20:43:01
crossReference	[DatabaseIdentifier:12668237] RHEA:52357
dbId	176517
displayName	SULTs transfer (SO4)2- group to PREG
edited	[InstanceEdit:176810] D'Eustachio, P, 2006-03-11 18:40:17
eventOf	[Pathway:R-HSA-156584] Cytosolic sulfonation of small molecules - Homo sapiens
followingEvent	[Reaction:R-HSA-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate - Homo sapiens
input	[SimpleEntity:R-ALL-158471] PAPS [cytosol] [SimpleEntity:R-ALL-193103] PREG [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:176579] Expression and characterization of the human 3 beta-hydroxysteroid sulfotransferases (SULT2B1a and SULT2B1b) [LiteratureReference:176485] Mutational analysis of human hydroxysteroid sulfotransferase SULT2B1 isoforms reveals that exon 1B of the SULT2B1 gene produces cholesterol sulfotransferase, whereas exon 1A yields pregnenolone sulfotransferase
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	SULTs transfer (SO4)2- group to PREG pregnenolone + PAPS => pregnenolone sulfate + PAP
orthologousEvent	[Reaction:R-CEL-176517] SULTs transfer (SO4)2- group to PREG - Caenorhabditis elegans [Reaction:R-GGA-176517] SULTs transfer (SO4)2- group to PREG - Gallus gallus [Reaction:R-XTR-176517] SULTs transfer (SO4)2- group to PREG - Xenopus tropicalis [Reaction:R-DRE-176517] SULTs transfer (SO4)2- group to PREG - Danio rerio [Reaction:R-SSC-176517] SULTs transfer (SO4)2- group to PREG - Sus scrofa [Reaction:R-BTA-176517] SULTs transfer (SO4)2- group to PREG - Bos taurus [Reaction:R-CFA-176517] SULTs transfer (SO4)2- group to PREG - Canis familiaris [Reaction:R-RNO-176517] SULTs transfer (SO4)2- group to PREG - Rattus norvegicus [Reaction:R-MMU-176517] SULTs transfer (SO4)2- group to PREG - Mus musculus
output	[SimpleEntity:R-ALL-158466] PAP [cytosol] [SimpleEntity:R-ALL-176665] PREGS [cytosol]
precedingEvent	[Reaction:R-HSA-174389] PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS - Homo sapiens
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-176517
summation	[Summation:176625] The sulfonation of pregnenolone (PREG) is catalyzed by both ...
updateTrackers	[UpdateTracker:9788096] Update Tracker - [Reaction:176517] SULTs transfer (SO4)2- group to PREG - v44:[modifyText] [UpdateTracker:9788772] Update Tracker - [Reaction:176517] SULTs transfer (SO4)2- group to PREG - v40:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9788096] Update Tracker - [Reaction:176517] SULTs transfer (SO4)2- group to PREG - v44:[modifyText] [UpdateTracker:9788772] Update Tracker - [Reaction:176517] SULTs transfer (SO4)2- group to PREG - v40:[add_removeInput]
(precedingEvent)	[Reaction:R-HSA-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
(hasEvent)	[Pathway:R-HSA-156584] Cytosolic sulfonation of small molecules