Reactome | LDL [extracellular region]

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LDL [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-HSA-176866] Lp(a) [extracellular region] - Homo sapiens [Complex:R-HSA-8933254] LSR trimer:LDL [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-171122] LDL + LDLR => LDL:LDLR complex - Homo sapiens [Reaction:R-HSA-176879] apolipoprotein(a) + LDL => Lp(a) - Homo sapiens [Reaction:R-HSA-203130] OLR1 binds to oxidized LDL - Homo sapiens [Reaction:R-HSA-432121] LDL binds to LRP8 - Homo sapiens [Reaction:R-HSA-8933258] LSR trimer binds LDL - Homo sapiens [Reaction:R-HSA-266350] CETP-mediated lipid exchange: LDL gains cholesterol ester - Homo sapiens
created	[InstanceEdit:171140] D'Eustachio, P, 2006-01-28 18:01:52
dbId	171131
displayName	LDL [extracellular region]
hasComponent	[EntityWithAccessionedSequence:R-HSA-171065] APOB(28-4563) [extracellular region] 1500 × [SimpleEntity:R-ALL-171076] CHEST [extracellular region] 670 × [SimpleEntity:R-ALL-171149] CHOL [extracellular region] 690 × [SimpleEntity:R-ALL-171066] PL [extracellular region] 170 × [SimpleEntity:R-ALL-171126] TAGs [extracellular region]
inDisease	false
inferredTo	[Complex:R-MMU-171131] LDL [extracellular region] - Mus musculus [Complex:R-RNO-171131] LDL [extracellular region] - Rattus norvegicus [Complex:R-CFA-171131] LDL [extracellular region] - Canis familiaris [Complex:R-BTA-171131] LDL [extracellular region] - Bos taurus [Complex:R-SSC-171131] LDL [extracellular region] - Sus scrofa [Complex:R-GGA-171131] LDL [extracellular region] - Gallus gallus
memberOf	[DefinedSet:R-HSA-2197637] Ligands of SCARB1 [extracellular region] - Homo sapiens [DefinedSet:R-HSA-2512795] Endocytosed Ligands of SCARB1 [extracellular region] - Homo sapiens [CandidateSet:R-HSA-9707486] LDL,HDL [extracellular region] - Homo sapiens
name	LDL low-density lipoprotein complex
positivelyRegulates	[PositiveRegulation:R-HSA-9006351] Positive regulation by 'LDL [extracellular region]'
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-171131
summation	[Summation:171110] LDL (low density lipoproteins) are complexes of a single mol...

Referrals

(hasComponent)	[Complex:R-HSA-8933254] LSR trimer:LDL [plasma membrane] [Complex:R-HSA-176866] Lp(a) [extracellular region] [Complex:R-HSA-266339] LDL:cholesterol ester [extracellular region] [Complex:R-HSA-203127] OLR1 bound to oxidized LDL [plasma membrane] [Complex:R-HSA-432133] LDL:p-LRP8 [plasma membrane] [Complex:R-HSA-432119] LDL:LRP8 [plasma membrane]
(input)	[Reaction:R-HSA-8933258] LSR trimer binds LDL [Reaction:R-HSA-171122] LDL + LDLR => LDL:LDLR complex [Reaction:R-HSA-176879] apolipoprotein(a) + LDL => Lp(a) [Reaction:R-HSA-266350] CETP-mediated lipid exchange: LDL gains cholesterol ester [Reaction:R-HSA-203130] OLR1 binds to oxidized LDL [Reaction:R-HSA-432121] LDL binds to LRP8
(hasMember)	[DefinedSet:R-HSA-2197637] Ligands of SCARB1 [extracellular region] [DefinedSet:R-HSA-2512795] Endocytosed Ligands of SCARB1 [extracellular region] [CandidateSet:R-HSA-9707486] LDL,HDL [extracellular region]
(regulator)	[PositiveRegulation:R-HSA-9006351] Positive regulation by 'LDL [extracellular region]'

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