Reactome | MuvB complex [nucleoplasm]

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MuvB complex [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-4088308] p-T611,S730,S739-FOXM1:MuvB:MYBL2:CCNB1 Gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-1362270] Phosphorylation of LIN52 component of MuvB by DYRK1A - Homo sapiens [Reaction:R-HSA-4088307] FOXM1 binds CCNB1 promoter - Homo sapiens [Reaction:R-HSA-4088306] FOXM1 binds PLK1 promoter - Homo sapiens [Reaction:R-HSA-4088309] FOXM1 binds CCNB2 promoter - Homo sapiens
created	[InstanceEdit:1362249] Orlic-Milacic, Marija, 2011-06-07
dbId	1362248
displayName	MuvB complex [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-389101] LIN37 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-389107] LIN52 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-389103] LIN54 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-389108] LIN9 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-212223] RBBP4 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-1362248] MuvB complex [nucleoplasm] - Mus musculus [Complex:R-RNO-1362248] MuvB complex [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-1362248] MuvB complex [nucleoplasm] - Canis familiaris [Complex:R-BTA-1362248] MuvB complex [nucleoplasm] - Bos taurus [Complex:R-SSC-1362248] MuvB complex [nucleoplasm] - Sus scrofa [Complex:R-DRE-1362248] MuvB complex [nucleoplasm] - Danio rerio [Complex:R-XTR-1362248] MuvB complex [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-1362248] MuvB complex [nucleoplasm] - Gallus gallus [Complex:R-DME-1362248] MuvB complex [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-1362248] MuvB complex [nucleoplasm] - Caenorhabditis elegans
isChimeric	false
maxDepth	2
name	MuvB complex LIN9:LIN37:LIN52:LIN54:RBBP4
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1362248

Referrals

(activeUnit)	[PositiveGeneExpressionRegulation:R-HSA-4088312] Positive gene expression regulation by 'p-T611,S730,S739-FOXM1:MuvB:MYBL2:CCNB1 Gene [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-4088302] Positive gene expression regulation by 'p-T611,S730,S739-FOXM1:MuvB:MYBL2:PLK1 Gene [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-4088296] Positive gene expression regulation by 'p-T611,S730,S739-FOXM1:MuvB:MYBL2:CCNB2 Gene [nucleoplasm]'
(hasComponent)	[Complex:R-HSA-4088308] p-T611,S730,S739-FOXM1:MuvB:MYBL2:CCNB1 Gene [nucleoplasm] [Complex:R-HSA-4088300] p-T611,S730,S739-FOXM1:MuvB:MYBL2:PLK1 Gene [nucleoplasm] [Complex:R-HSA-4088297] p-T611,S730,S739-FOXM1:MuvB:MYBL2:CCNB2 Gene [nucleoplasm]
(input)	[Reaction:R-HSA-4088307] FOXM1 binds CCNB1 promoter [Reaction:R-HSA-4088306] FOXM1 binds PLK1 promoter [Reaction:R-HSA-1362270] Phosphorylation of LIN52 component of MuvB by DYRK1A [Reaction:R-HSA-4088309] FOXM1 binds CCNB2 promoter

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