Reactome | FIH1:AscH-:Fe2+ dimer [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:1234170] 2-oxoglutarate-dependent dioxygenase activity of FIH1:AscH-:Fe2+ dimer [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1235001] May, B, 2011-03-19
dbId	1235007
displayName	FIH1:AscH-:Fe2+ dimer [cytosol]
hasComponent	2 × [Complex:R-HSA-9640410] FIH1:AscH-:Fe2+ [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-1235007] FIH1:AscH-:Fe2+ dimer [cytosol] - Mus musculus [Complex:R-RNO-1235007] FIH1:AscH-:Fe2+ dimer [cytosol] - Rattus norvegicus [Complex:R-CFA-1235007] FIH1:AscH-:Fe2+ dimer [cytosol] - Canis familiaris [Complex:R-BTA-1235007] FIH1:AscH-:Fe2+ dimer [cytosol] - Bos taurus [Complex:R-SSC-1235007] FIH1:AscH-:Fe2+ dimer [cytosol] - Sus scrofa [Complex:R-DRE-1235007] FIH1:AscH-:Fe2+ dimer [cytosol] - Danio rerio [Complex:R-XTR-1235007] FIH1:AscH-:Fe2+ dimer [cytosol] - Xenopus tropicalis [Complex:R-GGA-1235007] FIH1:AscH-:Fe2+ dimer [cytosol] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:1234094] Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity
maxDepth	3
modified	[InstanceEdit:9640409] Jassal, Bijay, 2019-03-26
name	FIH1:AscH-:Fe2+ dimer HIF1AN (FIH1) Homodimer
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1235007
updateTrackers	[UpdateTracker:9900432] Update Tracker - [Complex:1235007] FIH1:AscH-:Fe2+ dimer [cytosol] - v69:[add_removeHasComponent, modifyName]

(updatedInstance)	[UpdateTracker:9900432] Update Tracker - [Complex:1235007] FIH1:AscH-:Fe2+ dimer [cytosol] - v69:[add_removeHasComponent, modifyName]
(physicalEntity)	[CatalystActivity:1234170] 2-oxoglutarate-dependent dioxygenase activity of FIH1:AscH-:Fe2+ dimer [cytosol]