Reactome | Platelet degranulation

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Platelet degranulation Show undefined attributes

created	[InstanceEdit:141659] de Bono, B, Pace, N.P., Farndale, R, 2004-09-25 17:06:19
dbId	114608
displayName	Platelet degranulation
eventOf	[Pathway:R-HSA-76005] Response to elevated platelet cytosolic Ca2+ - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:263000] platelet degranulation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-429157] ABCC4 accumulation of dense granule contents - Homo sapiens [Reaction:R-HSA-481009] Exocytosis of platelet dense granule content - Homo sapiens [Reaction:R-HSA-481010] Surface deployment of platelet dense granule membrane components - Homo sapiens [Reaction:R-HSA-481007] Exocytosis of platelet alpha granule contents - Homo sapiens [Reaction:R-HSA-481044] Surface deployment of platelet alpha granule membrane components - Homo sapiens [Reaction:R-HSA-482772] Release of platelet cytosolic components - Homo sapiens [Reaction:R-HSA-482775] Release of (inferred) platelet cytosolic components - Homo sapiens [Reaction:R-HSA-482770] Release of platelet secretory granule components - Homo sapiens [Reaction:R-HSA-350745] Release of Calumenin - Homo sapiens [Reaction:R-HSA-351323] Release of 78 kDa glucose-regulated protein - Homo sapiens [Reaction:R-HSA-351341] Exocytosis of Proactivator polypeptide - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2021-06-14
literatureReference	[Book:427251] 9780521802611 Platelets in thrombotic and non-thrombotic disorders. Gresele, P [LiteratureReference:349781] Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions
maxDepth	2
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Platelet degranulation
orthologousEvent	[Pathway:R-PFA-114608] Platelet degranulation - Plasmodium falciparum [Pathway:R-SCE-114608] Platelet degranulation - Saccharomyces cerevisiae [Pathway:R-SPO-114608] Platelet degranulation - Schizosaccharomyces pombe [Pathway:R-DDI-114608] Platelet degranulation - Dictyostelium discoideum [Pathway:R-CEL-114608] Platelet degranulation - Caenorhabditis elegans [Pathway:R-DME-114608] Platelet degranulation - Drosophila melanogaster [Pathway:R-GGA-114608] Platelet degranulation - Gallus gallus [Pathway:R-XTR-114608] Platelet degranulation - Xenopus tropicalis [Pathway:R-DRE-114608] Platelet degranulation - Danio rerio [Pathway:R-SSC-114608] Platelet degranulation - Sus scrofa [Pathway:R-BTA-114608] Platelet degranulation - Bos taurus [Pathway:R-CFA-114608] Platelet degranulation - Canis familiaris [Pathway:R-RNO-114608] Platelet degranulation - Rattus norvegicus [Pathway:R-MMU-114608] Platelet degranulation - Mus musculus
releaseDate	2004-10-27
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-114608
summation	[Summation:419666] Platelets function as exocytotic cells, secreting a plethora...
updateTrackers	[UpdateTracker:9783071] Update Tracker - [Pathway:114608] Platelet degranulation - v57:[modifyText, updateContainedRLE] [UpdateTracker:9782688] Update Tracker - [Pathway:114608] Platelet degranulation - v59:[updateContainedRLE] [UpdateTracker:9776117] Update Tracker - [Pathway:114608] Platelet degranulation - v77:[updateContainedRLE] [UpdateTracker:9790745] Update Tracker - [Pathway:114608] Platelet degranulation - v33:[addLiteratureReference] [UpdateTracker:9789062] Update Tracker - [Pathway:114608] Platelet degranulation - v39:[removeHasEvent] [UpdateTracker:9791505] Update Tracker - [Pathway:114608] Platelet degranulation - v29:[addSummation] [UpdateTracker:9790034] Update Tracker - [Pathway:114608] Platelet degranulation - v35:[updateContainedRLE] [UpdateTracker:9791221] Update Tracker - [Pathway:114608] Platelet degranulation - v32:[addLiteratureReference, add_removeHasEvent, modifyText] [UpdateTracker:9790278] Update Tracker - [Pathway:114608] Platelet degranulation - v34:[addHasEvent, updateContainedRLE]

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[Pathway:R-HSA-76005] Response to elevated platelet cytosolic Ca2+

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