Reactome | PD-L1(CD274) glycosylation and translocation to plasma membrane

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PD-L1(CD274) glycosylation and translocation to plasma membrane Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10828527
displayName	PD-L1(CD274) glycosylation and translocation to plasma membrane
eventOf	[Pathway:R-GGA-9909615] Regulation of PD-L1(CD274) Post-translational modification - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-9931286] CD274 N-linked glycosylation in ER - Gallus gallus [Reaction:R-GGA-9931290] IL6-activated JAK1 phosphorylates CD274 - Gallus gallus [BlackBoxEvent:R-GGA-9931262] Transport of N-glycosylated CD274 to Golgi - Gallus gallus [Reaction:R-GGA-9931297] B3GNT3 mediated CD274 glycosylation in Golgi - Gallus gallus [Reaction:R-GGA-9931430] MIB2-mediated K63-ubiquitination of CD274 - Gallus gallus [Reaction:R-GGA-9931288] K63-Ub-polyLacNac-Glycosylated CD274 transport to plasma membrane - Gallus gallus [Reaction:R-GGA-9936162] PD-1 binds PD-L1,PD-L2 - Gallus gallus
inferredFrom	[Pathway:R-HSA-9931295] PD-L1(CD274) glycosylation and translocation to plasma membrane - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	PD-L1(CD274) glycosylation and translocation to plasma membrane
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-9931295
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9909615] Regulation of PD-L1(CD274) Post-translational modification
(inferredTo)	[Pathway:R-HSA-9931295] PD-L1(CD274) glycosylation and translocation to plasma membrane

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