Reactome | OADH complex synthesizes glutaryl-CoA from 2-OA

Schema > Pathway > Entries

OADH complex synthesizes glutaryl-CoA from 2-OA Show undefined attributes

compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10828493
displayName	OADH complex synthesizes glutaryl-CoA from 2-OA
eventOf	[Pathway:R-GGA-71064] Lysine catabolism - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-9858321] DHTKD1 dimer decarboxylates 2-OA - Gallus gallus [Reaction:R-GGA-9858590] DLST transfers glutaryl to CoA - Gallus gallus [Reaction:R-GGA-9858589] DLD dimer dehydrogenates dihydrolipoyl - Gallus gallus
inferredFrom	[Pathway:R-HSA-9858328] OADH complex synthesizes glutaryl-CoA from 2-OA - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	OADH complex synthesizes glutaryl-CoA from 2-OA alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ Oxidative decarboxylation of alpha-ketoadipate to glutaryl CoA by alpha-ketoglutarate dehydrogenase
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-9858328
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-71064] Lysine catabolism
(inferredTo)	[Pathway:R-HSA-9858328] OADH complex synthesizes glutaryl-CoA from 2-OA

© 2026 Reactome

Cite Us!