Reactome | Active LTK binds IRS1

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Active LTK binds IRS1 Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10821373
displayName	Active LTK binds IRS1
eventOf	[Pathway:R-GGA-9842663] Signaling by LTK - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-9842666] Active LTK phosphorylates IRS1 - Gallus gallus
inferredFrom	[Reaction:R-HSA-9842671] Active LTK binds IRS1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-GGA-74769] LOC107051846 [cytosol] [Complex:R-GGA-9842590] p-5Y LTK dimer:ALKAL1,2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Active LTK binds IRS1
output	[Complex:R-GGA-9842600] Active LTK:IRS1 [plasma membrane]
precedingEvent	[Reaction:R-GGA-9842648] Autophosphorylation of LTK dimer:ALKAL1,2 - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-9842671
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9842663] Signaling by LTK
(precedingEvent)	[Reaction:R-GGA-9842666] Active LTK phosphorylates IRS1
(inferredTo)	[Reaction:R-HSA-9842671] Active LTK binds IRS1

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