Reactome | FXa binds SERPINC1:HS

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FXa binds SERPINC1:HS Show undefined attributes

catalystActivity	[CatalystActivity:10820460] serine-type endopeptidase inhibitor activity of SERPINC1:HSPGs [plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10820462
displayName	FXa binds SERPINC1:HS
eventOf	[Pathway:R-GGA-9769739] Regulation of clotting cascade - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9823284] FXa binds SERPINC1:HS - Homo sapiens
input	[Complex:R-GGA-140689] factor Xa [extracellular region] [Complex:R-GGA-9823297] SERPINC1:HSPGs [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	FXa binds SERPINC1:HS factor Xa + antithrombin III:heparan sulfate -> factor Xa:antithrombin III:heparan sulfate
output	[Complex:R-GGA-9823281] FXa:SERPINC1:HS [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-9823284
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9769739] Regulation of clotting cascade
(inferredTo)	[Reaction:R-HSA-9823284] FXa binds SERPINC1:HS

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