Reactome | ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-GGA-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-9755507] UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10819217
displayName	ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol]
hasComponent	2 × [Complex:R-GGA-8932333] KEAP1:NEDD8-CUL3:RBX1 [cytosol] [EntityWithAccessionedSequence:R-GGA-9758077] NFE2L2 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9755498] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Homo sapiens
maxDepth	3
name	ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1
producedByEvent	[Reaction:R-GGA-9755505] KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-9755498
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-GGA-9755507] UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex
(output)	[Reaction:R-GGA-9755505] KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2
(hasComponent)	[Complex:R-GGA-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol]
(inferredTo)	[Complex:R-HSA-9755498] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol]

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