Reactome | SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA

Schema > Reaction > Entries

SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA Show undefined attributes

catalystActivity	[CatalystActivity:10746100] long-chain fatty acid-CoA ligase activity of SLC27A2 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10818955
displayName	SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA
eventOf	[Pathway:R-GGA-75105] Fatty acyl-CoA biosynthesis - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-9734540] ACLY tetramer binds ETC-1002-CoA - Gallus gallus
inferredFrom	[Reaction:R-HSA-9734535] SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [ChemicalDrug:R-ALL-9734538] bempedoic acid [cytosol] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] [ChemicalDrug:R-ALL-9734541] ETC-1002-CoA [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-9734535
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-75105] Fatty acyl-CoA biosynthesis
(precedingEvent)	[Reaction:R-GGA-9734540] ACLY tetramer binds ETC-1002-CoA
(inferredTo)	[Reaction:R-HSA-9734535] SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA

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