Reactome | NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP

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NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP Show undefined attributes

catalystActivity	[CatalystActivity:10818873] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides of NUDT1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10818877
displayName	NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP
eventOf	[Pathway:R-GGA-2393930] Phosphate bond hydrolysis by NUDT proteins - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-9731661] MAPDA hydrolyzes N6-methyl-dAMP to dIMP and methylamine - Gallus gallus [Reaction:R-GGA-71732] PPA1 hydrolyzes pyrophosphate to orthophosphate - Gallus gallus
inferredFrom	[Reaction:R-HSA-9731613] NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-9731628] N(6)-methyl-dATP(4-) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP N(6)-methyl-dATP + H2O => N(6)-methyl-dAMP + diphosphate + H(+)
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-9731609] N(6)-methyl-dAMP(2-) [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-9731613
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-GGA-71732] PPA1 hydrolyzes pyrophosphate to orthophosphate [Reaction:R-GGA-9731661] MAPDA hydrolyzes N6-methyl-dAMP to dIMP and methylamine
(hasEvent)	[Pathway:R-GGA-2393930] Phosphate bond hydrolysis by NUDT proteins
(inferredTo)	[Reaction:R-HSA-9731613] NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP

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