Reactome | Formation of the MLL4 complex

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10817501
displayName	Formation of the MLL4 complex
eventOf	[Pathway:R-GGA-9772755] Formation of WDR5-containing histone-modifying complexes - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9676268] Formation of the MLL4 complex - Homo sapiens
input	[EntityWithAccessionedSequence:R-GGA-1183219] KMT2D [nucleoplasm] [Complex:R-GGA-9675213] WRAD complex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Formation of the MLL4 complex
output	[Complex:R-GGA-9676261] MLL4 complex [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-9676268
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-9772755] Formation of WDR5-containing histone-modifying complexes
(inferredTo)	[Reaction:R-HSA-9676268] Formation of the MLL4 complex

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