Reactome | TAX1BP1:TNFAIP3 [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10796542] ubiquitin-protein transferase activity of TAX1BP1:TNFAIP3 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-GGA-5693059] TNF-alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4:TAX1BP1:TNFAIP3 [plasma membrane] - Gallus gallus [Complex:R-GGA-937333] TAX1BP1:TNFAIP3:TBK1/IKBKE [cytosol] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-5693055] TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes - Gallus gallus [Reaction:R-GGA-937337] TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10764419
displayName	TAX1BP1:TNFAIP3 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-GGA-937346] TAX1BP1 [cytosol] [EntityWithAccessionedSequence:R-GGA-688989] TNFAIP3 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-937339] TAX1BP1:TNFAIP3 [cytosol] - Homo sapiens
maxDepth	2
name	TAX1BP1:TNFAIP3
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-937339
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-GGA-5693055] TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes [Reaction:R-GGA-937337] TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination
(hasComponent)	[Complex:R-GGA-5693059] TNF-alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4:TAX1BP1:TNFAIP3 [plasma membrane] [Complex:R-GGA-937333] TAX1BP1:TNFAIP3:TBK1/IKBKE [cytosol]
(physicalEntity)	[CatalystActivity:10796542] ubiquitin-protein transferase activity of TAX1BP1:TNFAIP3 [cytosol]
(inferredTo)	[Complex:R-HSA-937339] TAX1BP1:TNFAIP3 [cytosol]