Reactome | Interleukin-5 receptor alpha subunit binds Interleukin-5

Schema > Reaction > Entries

Interleukin-5 receptor alpha subunit binds Interleukin-5 Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10763595
displayName	Interleukin-5 receptor alpha subunit binds Interleukin-5
eventOf	[Pathway:R-GGA-512988] Interleukin-3, Interleukin-5 and GM-CSF signaling - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-913370] Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2 - Gallus gallus
inferredFrom	[Reaction:R-HSA-913456] Interleukin-5 receptor alpha subunit binds Interleukin-5 - Homo sapiens
input	[Complex:R-GGA-913383] IL5 homodimer [extracellular region] [EntityWithAccessionedSequence:R-GGA-450072] IL5RA [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Interleukin-5 receptor alpha subunit binds Interleukin-5
output	[Complex:R-GGA-450056] IL5 homodimer:IL5RA [plasma membrane]
precedingEvent	[Reaction:R-GGA-913446] Interleukin-5 is a homodimer - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-913456
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-512988] Interleukin-3, Interleukin-5 and GM-CSF signaling
(precedingEvent)	[Reaction:R-GGA-913370] Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2
(inferredTo)	[Reaction:R-HSA-913456] Interleukin-5 receptor alpha subunit binds Interleukin-5

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