Reactome | ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators

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ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators Show undefined attributes

category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10815839
displayName	ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
eventOf	[Pathway:R-GGA-9018519] Estrogen-dependent gene expression - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-9038163] ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators - Homo sapiens
input	[Complex:R-GGA-9038156] ESR1:ER:PGR:P4 [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-453074] FOXA1 [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-996768] GATA3 [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-4086031] NRIP1 [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-3322363] TLE3 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
output	[Complex:R-GGA-9038159] ESR1:ESTG:PGR:P4:FOXA1:GATA3:TLE3:NRIP:EP300 [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-GGA-9038161] Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG - Gallus gallus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49591] Gallus gallus
stId	R-GGA-9038163
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9018519] Estrogen-dependent gene expression
(inferredTo)	[BlackBoxEvent:R-HSA-9038163] ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators

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