Reactome | 27-hydroxysterol binds ESR1, ESR2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10815822
displayName	27-hydroxysterol binds ESR1, ESR2
eventOf	[Pathway:R-GGA-8939211] ESR-mediated signaling - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9038029] 27-hydroxysterol binds ESR1, ESR2 - Homo sapiens
input	[SimpleEntity:R-ALL-9024328] 27-OH-CHOL [nucleoplasm] [DefinedSet:R-GGA-8939172] ESR1,2 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	27-hydroxysterol binds ESR1, ESR2
output	[Complex:R-GGA-9038025] 27-OH-CHOL:ESR1,2 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-9038029
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-8939211] ESR-mediated signaling
(inferredTo)	[Reaction:R-HSA-9038029] 27-hydroxysterol binds ESR1, ESR2

Cite Us!