Reactome | Biosynthesis of E-series 18(R)-resolvins

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Biosynthesis of E-series 18(R)-resolvins Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10828247
displayName	Biosynthesis of E-series 18(R)-resolvins
eventOf	[Pathway:R-GGA-9018679] Biosynthesis of EPA-derived SPMs - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:81415] long-chain fatty acid biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-9018895] GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE - Gallus gallus [Reaction:R-GGA-9018863] ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE - Gallus gallus [Reaction:R-GGA-9018894] ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE - Gallus gallus [Reaction:R-GGA-9018877] LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 - Gallus gallus
inferredFrom	[Pathway:R-HSA-9023661] Biosynthesis of E-series 18(R)-resolvins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Biosynthesis of E-series 18(R)-resolvins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-9023661
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9018679] Biosynthesis of EPA-derived SPMs
(inferredTo)	[Pathway:R-HSA-9023661] Biosynthesis of E-series 18(R)-resolvins

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