Reactome | Biosynthesis of D-series resolvins

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Biosynthesis of D-series resolvins Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10828253
displayName	Biosynthesis of D-series resolvins
eventOf	[Pathway:R-GGA-9018677] Biosynthesis of DHA-derived SPMs - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:81415] long-chain fatty acid biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-9020273] GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA - Gallus gallus [Reaction:R-GGA-9020264] ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA - Gallus gallus [Reaction:R-GGA-9020282] ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA - Gallus gallus [Reaction:R-GGA-9020255] ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA - Gallus gallus [Reaction:R-GGA-9020277] ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA - Gallus gallus [Reaction:R-GGA-9020258] LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 - Gallus gallus [Reaction:R-GGA-9020253] LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 - Gallus gallus [Reaction:R-GGA-9024766] HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 - Gallus gallus
inferredFrom	[Pathway:R-HSA-9018676] Biosynthesis of D-series resolvins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Biosynthesis of D-series resolvins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-9018676
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9018677] Biosynthesis of DHA-derived SPMs
(inferredTo)	[Pathway:R-HSA-9018676] Biosynthesis of D-series resolvins

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