Reactome | Signaling by Receptor Tyrosine Kinases

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Signaling by Receptor Tyrosine Kinases Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10825385
displayName	Signaling by Receptor Tyrosine Kinases
eventOf	[TopLevelPathway:R-GGA-162582] Signal Transduction - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-GGA-177929] Signaling by EGFR - Gallus gallus [Pathway:R-GGA-190236] Signaling by FGFR - Gallus gallus [Pathway:R-GGA-166520] Signaling by NTRKs - Gallus gallus [Pathway:R-GGA-74752] Signaling by Insulin receptor - Gallus gallus [Pathway:R-GGA-186797] Signaling by PDGF - Gallus gallus [Pathway:R-GGA-194138] Signaling by VEGF - Gallus gallus [Pathway:R-GGA-1433557] Signaling by SCF-KIT - Gallus gallus [Pathway:R-GGA-1227986] Signaling by ERBB2 - Gallus gallus [Pathway:R-GGA-1236394] Signaling by ERBB4 - Gallus gallus [Pathway:R-GGA-2404192] Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) - Gallus gallus [Pathway:R-GGA-6806834] Signaling by MET - Gallus gallus [Pathway:R-GGA-8852405] Signaling by MST1 - Gallus gallus [Pathway:R-GGA-201556] Signaling by ALK - Gallus gallus [Pathway:R-GGA-9842663] Signaling by LTK - Gallus gallus
inferredFrom	[Pathway:R-HSA-9006934] Signaling by Receptor Tyrosine Kinases - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	9
name	Signaling by Receptor Tyrosine Kinases
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-9006934
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-GGA-162582] Signal Transduction
(inferredTo)	[Pathway:R-HSA-9006934] Signaling by Receptor Tyrosine Kinases

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