Reactome | IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B

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IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10813556
displayName	IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B
eventOf	[Pathway:R-GGA-8985947] Interleukin-9 signaling - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-8985988] IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 - Gallus gallus
inferredFrom	[Reaction:R-HSA-8985929] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B - Homo sapiens
input	[Complex:R-GGA-8985997] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] [DefinedSet:R-GGA-1433551] STATs [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B STAT1, STAT3 or STAT5 bind IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3
output	[Complex:R-GGA-8985893] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane]
precedingEvent	[BlackBoxEvent:R-GGA-8985973] IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-8985929
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-8985947] Interleukin-9 signaling
(precedingEvent)	[Reaction:R-GGA-8985988] IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5
(inferredTo)	[Reaction:R-HSA-8985929] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B

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