Reactome | IL12B binds IL23A

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IL12B binds IL23A Show undefined attributes

catalystActivity	[CatalystActivity:10811289] protein disulfide isomerase activity of P4HB [endoplasmic reticulum lumen]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10811316
displayName	IL12B binds IL23A
eventOf	[Pathway:R-GGA-9020933] Interleukin-23 signaling - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8950183] IL12B binds IL23A - Homo sapiens
input	[EntityWithAccessionedSequence:R-GGA-8950126] IL12B [endoplasmic reticulum lumen] [EntityWithAccessionedSequence:R-GGA-8950224] IL23A [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	IL12B binds IL23A Interleukin-12 subunit beta binds Interleukin-23 subunit alpha forming Interleukin-23 Interleukin-12B binds Interleukin-23A forming Interleukin-23 Interleukin-12B binds Interleukin-23A
output	[Complex:R-GGA-8950275] IL12B:IL23A [endoplasmic reticulum lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-8950183
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9020933] Interleukin-23 signaling
(inferredTo)	[Reaction:R-HSA-8950183] IL12B binds IL23A

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