Reactome | PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol

Schema > Reaction > Entries

PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10809305] basic amino acid transmembrane transporter activity of PQLC2 [lysosomal membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:161320] lysosomal lumen [Compartment:17938] lysosomal membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10809307
displayName	PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol
eventOf	[Pathway:R-GGA-5223345] Miscellaneous transport and binding events - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-70899] histidine => urocanate + NH4+ - Gallus gallus
inferredFrom	[Reaction:R-HSA-8932851] PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol - Homo sapiens
input	[DefinedSet:R-ALL-8932838] L-Arg,L-His,L-Lys [lysosomal lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol
output	[DefinedSet:R-ALL-8932842] L-Arg,L-His,L-Lys [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-8932851
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-5223345] Miscellaneous transport and binding events
(precedingEvent)	[Reaction:R-GGA-70899] histidine => urocanate + NH4+
(inferredTo)	[Reaction:R-HSA-8932851] PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol

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