Reactome | SOCS-1 and SOCS-3 binds to p-JAK2

Schema > Reaction > Entries

SOCS-1 and SOCS-3 binds to p-JAK2 Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10762872
displayName	SOCS-1 and SOCS-3 binds to p-JAK2
eventOf	[Pathway:R-GGA-877312] Regulation of IFNG signaling - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-877269] SOCS-1 and SOCS-3 binds to p-JAK2 - Homo sapiens
input	[Complex:R-GGA-873811] IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] [DefinedSet:R-GGA-877267] SOCS-1 and SOCS-3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SOCS-1 and SOCS-3 binds to p-JAK2
output	[Complex:R-GGA-873821] IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane]
precedingEvent	[Reaction:R-GGA-873919] Phosphorylation of JAK2 - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-877269
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-877312] Regulation of IFNG signaling
(inferredTo)	[Reaction:R-HSA-877269] SOCS-1 and SOCS-3 binds to p-JAK2

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