Reactome | Insulin receptor recycling

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Insulin receptor recycling Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10825387
displayName	Insulin receptor recycling
eventOf	[Pathway:R-GGA-74752] Signaling by Insulin receptor - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2132726] insulin receptor recycling
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-74723] Endosome acidification - Gallus gallus [Reaction:R-GGA-74726] Dissociation of insulin from insulin receptor - Gallus gallus [BlackBoxEvent:R-GGA-74730] Insulin degradation - Gallus gallus [Reaction:R-GGA-74733] Insulin receptor de-phosphorylation - Gallus gallus [BlackBoxEvent:R-GGA-74734] Re-integration of insulin receptor into plasma membrane - Gallus gallus
inferredFrom	[Pathway:R-HSA-77387] Insulin receptor recycling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Insulin receptor recycling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-77387
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-74752] Signaling by Insulin receptor
(inferredTo)	[Pathway:R-HSA-77387] Insulin receptor recycling

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