Reactome | MRN [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-GGA-5687666] Extended microhomologous 3'-ssDNA overhangs-DSB:MRN [nucleoplasm] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-5682020] MRN complex binds shortened telomeres - Gallus gallus [Reaction:R-GGA-3785768] MRN complex binds DNA double strand breaks - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10737009
displayName	MRN [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-GGA-59544] MRE11 [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-75163] NBN [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-75160] RAD50 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-75164] MRN [nucleoplasm] - Homo sapiens
maxDepth	2
name	MRN
producedByEvent	[Reaction:R-GGA-75174] Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-75164
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-GGA-5687666] Extended microhomologous 3'-ssDNA overhangs-DSB:MRN [nucleoplasm] [Complex:R-GGA-5687467] Microhomologous 3'-ssDNA overhangs-DSB:MRN [nucleoplasm] [Complex:R-GGA-5687502] Annealed microhomologous 3'-ssDNA overhangs-DSB:MRN [nucleoplasm] [Complex:R-GGA-5687646] Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN [nucleoplasm] [Complex:R-GGA-5682022] Shortened telomere:MRN [nucleoplasm] [Complex:R-GGA-3785763] DNA DSBs:MRN [nucleoplasm]
(input)	[Reaction:R-GGA-5682020] MRN complex binds shortened telomeres [Reaction:R-GGA-3785768] MRN complex binds DNA double strand breaks
(output)	[Reaction:R-GGA-75174] Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction
(inferredTo)	[Complex:R-HSA-75164] MRN [nucleoplasm]

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