Reactome | conversion of 5,6-Dihydrothymine to 3-Ureidoisobutyrate

Schema > Reaction > Entries

conversion of 5,6-Dihydrothymine to 3-Ureidoisobutyrate Show undefined attributes

catalystActivity	[CatalystActivity:10735258] dihydropyrimidinase activity of DPYS tetramer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10735309
displayName	conversion of 5,6-Dihydrothymine to 3-Ureidoisobutyrate
eventOf	[Pathway:R-GGA-73621] Pyrimidine catabolism - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-73620] conversion of 3-Ureidoiosbutyrate to 3-Aminoisobutyrate - Gallus gallus
inferredFrom	[Reaction:R-HSA-73618] conversion of 5,6-Dihydrothymine to 3-Ureidoisobutyrate - Homo sapiens
input	[SimpleEntity:R-ALL-73541] 5,6-Dihydrothymine [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	conversion of 5,6-Dihydrothymine to 3-Ureidoisobutyrate 5,6-dihydrothymine + H2O => 3-(carbamoylamino)-2-methylpropanoate + H(+)
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73617] UIBA [cytosol]
precedingEvent	[Reaction:R-GGA-73616] reduction of thymine to form 5,6-Dihydrothymine - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-73618
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-73621] Pyrimidine catabolism
(precedingEvent)	[Reaction:R-GGA-73620] conversion of 3-Ureidoiosbutyrate to 3-Aminoisobutyrate
(inferredTo)	[Reaction:R-HSA-73618] conversion of 5,6-Dihydrothymine to 3-Ureidoisobutyrate

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