Reactome | eIF5B:GTP is hydrolyzed and released

Schema > Reaction > Entries

category	dissociation
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10735175
displayName	eIF5B:GTP is hydrolyzed and released
eventOf	[Pathway:R-GGA-72706] GTP hydrolysis and joining of the 60S ribosomal subunit - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-72671] eIF5B:GTP is hydrolyzed and released - Homo sapiens
input	[Complex:R-GGA-72504] 80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	eIF5B:GTP is hydrolyzed and released
output	[Complex:R-GGA-72505] 80S:Met-tRNAi:mRNA [cytosol] [Complex:R-GGA-72502] eIF5B:GDP [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-72671
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-72706] GTP hydrolysis and joining of the 60S ribosomal subunit
(inferredTo)	[Reaction:R-HSA-72671] eIF5B:GTP is hydrolyzed and released

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