Reactome | arginine + glycine => ornithine + guanidoacetate

Schema > Reaction > Entries

arginine + glycine => ornithine + guanidoacetate Show undefined attributes

catalystActivity	[CatalystActivity:10734307] glycine amidinotransferase activity of GATM dimer [mitochondrial intermembrane space]
category	transition
compartment	[Compartment:17927] mitochondrial intermembrane space
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10734309
displayName	arginine + glycine => ornithine + guanidoacetate
eventOf	[Pathway:R-GGA-71288] Creatine metabolism - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-71286] guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine - Gallus gallus
inferredFrom	[Reaction:R-HSA-71275] arginine + glycine => ornithine + guanidoacetate - Homo sapiens
input	[SimpleEntity:R-ALL-113545] Gly [mitochondrial intermembrane space] [SimpleEntity:R-ALL-113530] L-Arg [mitochondrial intermembrane space]
isInDisease	false
isInferred	true
maxDepth	1
name	arginine + glycine => ornithine + guanidoacetate L-arginine + glycine => guanidinoacetate + L-ornithine
output	[SimpleEntity:R-ALL-113543] GAA [mitochondrial intermembrane space] [SimpleEntity:R-ALL-113586] L-Orn [mitochondrial intermembrane space]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-71275
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-71288] Creatine metabolism
(precedingEvent)	[Reaction:R-GGA-71286] guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine
(inferredTo)	[Reaction:R-HSA-71275] arginine + glycine => ornithine + guanidoacetate

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