Reactome | D-methylmalonyl-CoA <=> L-methylmalonyl-CoA

Schema > Reaction > Entries

D-methylmalonyl-CoA <=> L-methylmalonyl-CoA Show undefined attributes

catalystActivity	[CatalystActivity:10734124] methylmalonyl-CoA epimerase activity of MCEE [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10734126
displayName	D-methylmalonyl-CoA <=> L-methylmalonyl-CoA
eventOf	[Pathway:R-GGA-71032] Propionyl-CoA catabolism - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-71010] MUT isomerises L-MM-CoA to SUCC-CoA - Gallus gallus
inferredFrom	[Reaction:R-HSA-71020] D-methylmalonyl-CoA <=> L-methylmalonyl-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-71019] MEMA-CoA [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	D-methylmalonyl-CoA <=> L-methylmalonyl-CoA (S)-methylmalonyl-CoA => (R)-methylmalonyl-CoA
output	[SimpleEntity:R-ALL-71009] L-MM-CoA [mitochondrial matrix]
precedingEvent	[Reaction:R-GGA-71031] propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-71020
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-71032] Propionyl-CoA catabolism
(precedingEvent)	[Reaction:R-GGA-71010] MUT isomerises L-MM-CoA to SUCC-CoA
(inferredTo)	[Reaction:R-HSA-71020] D-methylmalonyl-CoA <=> L-methylmalonyl-CoA

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