Reactome | Removal of the Flap Intermediate

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Removal of the Flap Intermediate Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10825127
displayName	Removal of the Flap Intermediate
eventOf	[Pathway:R-GGA-69183] Processive synthesis on the lagging strand - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-69140] RPA binds to the Flap - Gallus gallus [Reaction:R-GGA-69142] Recruitment of Dna2 endonuclease - Gallus gallus [Reaction:R-GGA-69144] Removal of RNA primer and dissociation of RPA and Dna2 - Gallus gallus [Reaction:R-GGA-69152] Removal of remaining Flap - Gallus gallus
inferredFrom	[Pathway:R-HSA-69166] Removal of the Flap Intermediate - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Removal of the Flap Intermediate
precedingEvent	[Reaction:R-GGA-69127] Formation of the Flap Intermediate - Gallus gallus
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-69166
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-69183] Processive synthesis on the lagging strand
(inferredTo)	[Pathway:R-HSA-69166] Removal of the Flap Intermediate

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