Reactome | DNA polymerase alpha:primase [nucleoplasm]

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DNA polymerase alpha:primase [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:10732843] DNA-directed DNA polymerase activity of DNA polymerase alpha:primase [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-GGA-68510] DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] - Gallus gallus [Complex:R-GGA-9668602] POLA:primase:G-strand extended telomere end [nucleoplasm] - Gallus gallus [Complex:R-GGA-68423] RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-68914] DNA polymerase alpha:primase binds at the origin - Gallus gallus [Reaction:R-GGA-9668597] DNA polymerase:primase binds G-strand of the telomere - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10732542
displayName	DNA polymerase alpha:primase [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-GGA-68487] POLA1 [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-68493] POLA2 [nucleoplasm] [Complex:R-GGA-9668812] PRIM1:PRIM2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-68507] DNA polymerase alpha:primase [nucleoplasm] - Homo sapiens
maxDepth	3
name	DNA polymerase alpha:primase
producedByEvent	[Reaction:R-GGA-174452] RFC binding displaces Pol Alpha on the C-strand of the telomere - Gallus gallus [Reaction:R-GGA-113504] Detection of damage during initiation of DNA synthesis in S-phase - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-68507
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(output)	[Reaction:R-GGA-113504] Detection of damage during initiation of DNA synthesis in S-phase [Reaction:R-GGA-174452] RFC binding displaces Pol Alpha on the C-strand of the telomere
(physicalEntity)	[CatalystActivity:10732843] DNA-directed DNA polymerase activity of DNA polymerase alpha:primase [nucleoplasm]
(activeUnit)	[CatalystActivity:10732567] DNA-directed RNA polymerase activity of DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] [CatalystActivity:10743711] DNA-directed DNA polymerase activity of RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm]
(input)	[Reaction:R-GGA-68914] DNA polymerase alpha:primase binds at the origin [Reaction:R-GGA-9668597] DNA polymerase:primase binds G-strand of the telomere
(hasComponent)	[Complex:R-GGA-68510] DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] [Complex:R-GGA-68423] RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] [Complex:R-GGA-9668602] POLA:primase:G-strand extended telomere end [nucleoplasm] [Complex:R-GGA-174434] RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm]
(inferredTo)	[Complex:R-HSA-68507] DNA polymerase alpha:primase [nucleoplasm]

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