Reactome | EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA

Schema > Reaction > Entries

EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA Show undefined attributes

catalystActivity	[CatalystActivity:10803670] 3-hydroxyacyl-CoA dehydratase activity of EHHADH [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10803672
displayName	EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA
eventOf	[Pathway:R-GGA-390247] Beta-oxidation of very long chain fatty acids - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-6809264] EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA - Gallus gallus [Reaction:R-GGA-390251] HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA - Gallus gallus
inferredFrom	[Reaction:R-HSA-6809263] EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-141343] H2O [peroxisomal matrix] [SimpleEntity:R-ALL-390249] trans-2,3-dehydrohexacosanoyl-CoA [peroxisomal matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (2E)-hexacosenoyl-CoA + H2O => (3R)-hydroxyhexacosanoyl-CoA trans-2,3-dehydrohexacosanoyl-CoA + H2O => 3-hydroxyhexacosanoyl-CoA (EHHADH)
output	[SimpleEntity:R-ALL-390248] 3-hydroxyhexacosanoyl-CoA [peroxisomal matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-6809263
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-390247] Beta-oxidation of very long chain fatty acids
(precedingEvent)	[Reaction:R-GGA-390251] HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA [Reaction:R-GGA-6809264] EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA
(inferredTo)	[Reaction:R-HSA-6809263] EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA

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