Reactome | Regulation of TP53 Activity through Acetylation

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Regulation of TP53 Activity through Acetylation Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10827975
displayName	Regulation of TP53 Activity through Acetylation
eventOf	[Pathway:R-GGA-5633007] Regulation of TP53 Activity - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:3132571] regulation of signal transduction by p53 class mediator
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-GGA-6805638] KAT6A acetylates TP53 - Gallus gallus [Reaction:R-GGA-6805640] AKT phosphorylates KAT6A - Gallus gallus [Reaction:R-GGA-6805650] MTA2-NuRD complex deacetylates TP53 - Gallus gallus [Pathway:R-GGA-6811555] PI5P Regulates TP53 Acetylation - Gallus gallus
inferredFrom	[Pathway:R-HSA-6804758] Regulation of TP53 Activity through Acetylation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Regulation of TP53 Activity through Acetylation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-6804758
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-5633007] Regulation of TP53 Activity
(inferredTo)	[Pathway:R-HSA-6804758] Regulation of TP53 Activity through Acetylation

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