Reactome | USP2:PolyUb,p-S166,S188-MDM2:PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10795735] cysteine-type deubiquitinase activity of USP2:PolyUb,p-S166,S188-MDM2:PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-GGA-5689972] USP2 deubiquitinates MDM2,MDM4 - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10795734
displayName	USP2:PolyUb,p-S166,S188-MDM2:PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm]
hasComponent	[Complex:R-GGA-6804937] PolyUb,p-S166,S188-MDM2:PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-5689946] USP2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-6782767] USP2:PolyUb,p-S166,S188-MDM2:PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm] - Homo sapiens
maxDepth	3
name	USP2:PolyUb,p-S166,S188-MDM2:PolyUb,p-S342,S367,S403-MDM4
producedByEvent	[Reaction:R-GGA-6805022] USP2 binds the heterodimer of MDM2 and MDM4 - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-6782767
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-GGA-5689972] USP2 deubiquitinates MDM2,MDM4
(physicalEntity)	[CatalystActivity:10795735] cysteine-type deubiquitinase activity of USP2:PolyUb,p-S166,S188-MDM2:PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm]
(output)	[Reaction:R-GGA-6805022] USP2 binds the heterodimer of MDM2 and MDM4
(inferredTo)	[Complex:R-HSA-6782767] USP2:PolyUb,p-S166,S188-MDM2:PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm]

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