Reactome | Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors

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Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors Show undefined attributes

catalystActivity	[CatalystActivity:10762496] ligand-gated monoatomic ion channel activity of O-acteylcholine bound to calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10762498
displayName	Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors
eventOf	[Pathway:R-GGA-629594] Highly calcium permeable postsynaptic nicotinic acetylcholine receptors - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-629595] Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors - Homo sapiens
input	[SimpleEntity:R-ALL-74112] Ca2+ [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors
output	[SimpleEntity:R-ALL-74016] Ca2+ [cytosol]
precedingEvent	[Reaction:R-GGA-629596] Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-629595
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-629594] Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
(inferredTo)	[Reaction:R-HSA-629595] Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors

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