Reactome | USP18 deubiquitinates TAK1:TAB1

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USP18 deubiquitinates TAK1:TAB1 Show undefined attributes

catalystActivity	[CatalystActivity:10797410] cysteine-type deubiquitinase activity of USP18:PolyUb-MAP3K7:TAB1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10797412
displayName	USP18 deubiquitinates TAK1:TAB1
eventOf	[Pathway:R-GGA-5689880] Ub-specific processing proteases - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5696534] USP18 deubiquitinates TAK1:TAB1 - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-GGA-6782977] USP18:PolyUb-MAP3K7:TAB1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	USP18 deubiquitinates TAK1:TAB1
output	[Complex:R-GGA-6782955] MAP3K7:TAB1 [cytosol] [DefinedSet:R-GGA-5689096] PolyUb [cytosol] [Complex:R-GGA-6782967] USP18:MAP3K7:TAB1 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-5696534
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-5689880] Ub-specific processing proteases
(inferredTo)	[Reaction:R-HSA-5696534] USP18 deubiquitinates TAK1:TAB1

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