Reactome | PPT1 hydrolyses palmitoylated proteins

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PPT1 hydrolyses palmitoylated proteins Show undefined attributes

catalystActivity	[CatalystActivity:10796012] palmitoyl-(protein) hydrolase activity of PPT1 [lysosomal lumen]
category	transition
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10796014
displayName	PPT1 hydrolyses palmitoylated proteins
eventOf	[Pathway:R-GGA-75105] Fatty acyl-CoA biosynthesis - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5690517] PPT1 hydrolyses palmitoylated proteins - Homo sapiens
input	[SimpleEntity:R-ALL-1605715] H2O [lysosomal lumen] [Complex:R-ALL-5690533] PALM:protein [lysosomal lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	PPT1 hydrolyses palmitoylated proteins H2O + S-hexadecanoyl-L-cysteinyl-(protein) => H(+) + hexadecanoate + L-cysteinyl-(protein)
output	[SimpleEntity:R-ALL-428040] H+ [lysosomal lumen] [SimpleEntity:R-ALL-5690516] PALM [lysosomal lumen] [SimpleEntity:R-ALL-6785219] protein [lysosomal lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-5690517
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-75105] Fatty acyl-CoA biosynthesis
(inferredTo)	[Reaction:R-HSA-5690517] PPT1 hydrolyses palmitoylated proteins

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