Reactome | p-Y142-H2AFX-Nucleosome [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-GGA-5693563] DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome [nucleoplasm] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-5693602] ATM recognizes H2AFX-Nucleosomes - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10794516
displayName	p-Y142-H2AFX-Nucleosome [nucleoplasm]
hasComponent	2 × [GenomeEncodedEntity:R-GGA-181914] Ghost homologue of HIST3H3 [nucleoplasm] 2 × [CandidateSet:R-GGA-181911] Histone H2B [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-GGA-4551308] Histone H4 [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-GGA-5683942] phospho-H2AX [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5683932] p-Y142-H2AFX-Nucleosome [nucleoplasm] - Homo sapiens
maxDepth	4
name	p-Y142-H2AFX-Nucleosome
producedByEvent	[Reaction:R-GGA-5683930] WICH phosphorylates H2AFX on Y142 - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-5683932
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-GGA-5693602] ATM recognizes H2AFX-Nucleosomes
(hasComponent)	[Complex:R-GGA-5693563] DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome [nucleoplasm]
(output)	[Reaction:R-GGA-5683930] WICH phosphorylates H2AFX on Y142
(inferredTo)	[Complex:R-HSA-5683932] p-Y142-H2AFX-Nucleosome [nucleoplasm]

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