Reactome | PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA

Schema > Reaction > Entries

PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA Show undefined attributes

catalystActivity	[CatalystActivity:10793984] 3-hydroxyacyl-CoA dehydratase activity of PTPLs [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10793986
displayName	PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA
eventOf	[Pathway:R-GGA-75876] Synthesis of very long-chain fatty acyl-CoAs - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Gallus gallus
inferredFrom	[Reaction:R-HSA-5676637] PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-5676631] VLC3HA-CoA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA
output	[SimpleEntity:R-ALL-5676634] 2,3-TE-CoA [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
precedingEvent	[Reaction:R-GGA-548818] HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-5676637
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-75876] Synthesis of very long-chain fatty acyl-CoAs
(precedingEvent)	[Reaction:R-GGA-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA
(inferredTo)	[Reaction:R-HSA-5676637] PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA

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