Reactome | MKL1 translocates from cytosol to the nucleus

Schema > Reaction > Entries

category	transition
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10793085
displayName	MKL1 translocates from cytosol to the nucleus
eventOf	[Pathway:R-GGA-5663220] RHO GTPases Activate Formins - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5665999] MKL1 translocates from cytosol to the nucleus - Homo sapiens
input	[EntityWithAccessionedSequence:R-GGA-5665975] MKL1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MKL1 translocates from cytosol to the nucleus
output	[EntityWithAccessionedSequence:R-GGA-3900220] MKL1 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-5665999
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-5663220] RHO GTPases Activate Formins
(inferredTo)	[Reaction:R-HSA-5665999] MKL1 translocates from cytosol to the nucleus

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